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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 353720Generated: October 26, 2026

2-(4-(4-Nitrophenyl)piperazin-1-yl)ethanol → 4-(2-Hydroxyethyl)-1-(4-isothiocyanatophenyl)piperazine

https://huagongshe.com/reaction/353720

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-(4-Nitrophenyl)piperazin-1-yl)ethanolHCID 2763936—
ReactantHCID 178418790HCID 178418790—
Product4-(2-Hydroxyethyl)-1-(4-isothiocyanatophenyl)piperazineHCID 9965125—

Reaction Steps

This compound was prepared from 4-(4-nitrophenyl)-1-piperazine-ethanol (Bionet Research Ltd.) using the hydrogenation and isothiocyanate-forming reactions used in Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06756374B2
Source datasetuspto-grants-2004_06
ORD IDord-dd344ec8e6544b27b76ae7a6c6558a41
Source noteuspto-grants-2004_06