HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Nitrophenyl)-1-piperazinepropanol → 4-(3-Hydroxypropyl)-1-(4-isothiocyanatophenyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Nitrophenyl)-1-piperazinepropanol | HCID 21958933 | — |
| Reactant | HCID 178418790 | HCID 178418790 | — |
| Product | 4-(3-Hydroxypropyl)-1-(4-isothiocyanatophenyl)piperazine | HCID 9965439 | — |
Reaction Steps
This compound was prepared from 4-(4-nitrophenyl)-1-piperazine-propanol (which can be prepared according to the procedure of Loewe and Mieth Arzneim.-Forsch. 1966, 16, 1306-1310) using the hydrogenation and isothiocyanate-forming reactions used in Example 4. MS (ES) MH+=277.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06756374B2 |
| Source dataset | uspto-grants-2004_06 |
| ORD ID | ord-ff863fd80ca14fec9d6f9cff1af253b6 |
| Source note | uspto-grants-2004_06 |