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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 353742Generated: October 27, 2026

Pyrrolidine → [4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl][3-nitro-4-(1-pyrrolidinyl)phenyl]methanone

https://huagongshe.com/reaction/353742

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant[4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl](4-chloro-3-nitrophenyl)methanoneHCID 10162409—
Product[4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl][3-nitro-4-(1-pyrrolidinyl)phenyl]methanoneHCID 21958936—

Reaction Steps

This compound was prepared from the compound of Example 15 and pyrrolidine by the procedure used in Example 57. Mass spectrum (ES) MH+=508.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06756374B2
Source datasetuspto-grants-2004_06
ORD IDord-8c869b42654f41d29e1d7c3592751375
Source noteuspto-grants-2004_06