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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 353745Generated: October 30, 2026

Piperidin-3-ylmethanol → racemic [4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl][3-nitro-4-[3-(hydroxymethyl)-1-piperidinyl]phenyl]methanone

https://huagongshe.com/reaction/353745

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidin-3-ylmethanolHCID 107308—
Reactant[4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl](4-chloro-3-nitrophenyl)methanoneHCID 10162409—
Productracemic [4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl][3-nitro-4-[3-(hydroxymethyl)-1-piperidinyl]phenyl]methanoneHCID 21958934—

Reaction Steps

This compound was prepared from the compound of Example 15 and racemic 3-piperidinemethanol (Aldrich) by the procedure used in Example 57. Mass spectrum (ES) MH+=552.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06756374B2
Source datasetuspto-grants-2004_06
ORD IDord-1cc6c8b3046f43459dcb3d3d83d809e2
Source noteuspto-grants-2004_06