Piperidin-4-ol → [4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl][3-nitro-4-(4-hydroxy-1-piperidinyl)phenyl]methanone

Participants

Role	Name	HCID	Charge
Reactant	Piperidin-4-ol	HCID 79341	—
Reactant	[4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl](4-chloro-3-nitrophenyl)methanone	HCID 10162409	—
Product	[4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl][3-nitro-4-(4-hydroxy-1-piperidinyl)phenyl]methanone	HCID 21958955	—

Reaction Steps

This compound was prepared from the compound of Example 15 and 4-piperidinol (Aldrich) by the procedure used in Example 57. Mass spectrum (ES) MH+=538.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06756374B2
Source dataset	uspto-grants-2004_06
ORD ID	ord-98ef799acc7d4456a89e05e6b2ca8f25
Source note	uspto-grants-2004_06