Cyanamide → {4-Amino-2-[4-(4-cyclopropylmethyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-fluoro-4-methoxy-phenyl)-methanone

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Cyanamide	HCID 9864	—
Edukt	3-Fluoro-4-methoxyphenacyl bromide	HCID 7061846	—
Edukt	1-(4-Isothiocyanatophenyl)-4-cyclopropylmethylpiperazine	HCID 21958916	—
Produkt	{4-Amino-2-[4-(4-cyclopropylmethyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-fluoro-4-methoxy-phenyl)-methanone	HCID 21958929	—

Reaktionsschritte

This compound was prepared from cyanamide, 1-(4-isothiocyanatophenyl)-4-cyclopropylmethylpiperazine (of Example 14G) and 2-bromo-1-(3-fluoro-4-methoxyphenyl)ethanone (of Example 13) following the procedure used in Example 24. Mass spectrum (ES) MH+=482.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US06756374B2
Quelldatensatz	uspto-grants-2004_06
ORD ID	ord-4870495c53f4459c8c0bca602ce18fca
Quellennotiz	uspto-grants-2004_06