Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | HCID 23511438 | HCID 23511438 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 23511436 | HCID 23511436 | — |
Reaction Steps
To 2-[2-(Methyl-quinolin-2-ylmethyl-amino)-ethyl]-isoindole-1,3-dione (1 eq) in Ethanol was added hydrazine (2 eq). A Reflux condenser was attached and the solution was heated 65° C. for 19 hours. The solution was then filtered, concentrated, and co-evaporated from toluene to yield N1-Methyl-N1-quinolin-2-ylmethyl-ethane-1,2-diamine in quantitative yield as a dark oil. MH+(216).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06756359B2 |
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| Source dataset | uspto-grants-2004_06 |
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| ORD ID | ord-c522c4bbe7d64eeaba20c9205837bfbf |
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| Source note | uspto-grants-2004_06 |
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