反应详情

Under an argon atmosphere, 1,5-diaminopentane (25 g, 0.24 mol) and benzamide (9.9 g, 0.081 mol) were combined and heated at reflux overnight. The reaction mixture was concentrated under vacuum to remove the excess diamine. The residue was distilled at about 210° C. at 12 torr (16×102 pascals) to provide 11.8 g of N-(5-aminopentyl)benzamide as a colorless oil.

1. temperatureheated
2. temperatureat reflux overnight
3. concentrationThe reaction mixture was concentrated under vacuum
4. customto remove the excess diamine
5. distillationThe residue was distilled at about 210° C. at 12 torr (16×102 pascals)