Ethyl (morpholin-4-ylcarbonothioyl)carbamate → {[1-(4-Cyano-1-propyl-piperidin-4-ylcarbamoyl)-3,3-dimethyl-butylimino]-morpholin-4-yl-methyl}-carbamic acid ethyl ester

Participants

Role	Name	HCID	Charge
Reactant	Ethyl (morpholin-4-ylcarbonothioyl)carbamate	HCID 2824559	—
Reactant	2-Amino-4,4-dimethyl-pentanoic acid(4-cyano-1-propyl-piperidin-4-yl)amide bis hydrochloride salt	HCID 86585201	—
Product	{[1-(4-Cyano-1-propyl-piperidin-4-ylcarbamoyl)-3,3-dimethyl-butylimino]-morpholin-4-yl-methyl}-carbamic acid ethyl ester	HCID 22091417	—

Reaction Steps

The title compound was prepared starting from (Morpholine-4-carbothioyl)-carbamic acid ethyl ester and 2-amino -4,4-dimethyl-pentanoic acid (4-cyano-1-propyl-piperidin-4-yl)amide bis hydrochloride salt according to the procedure from Example 76. MS, m/z 460=M+1.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06756372B2
Source dataset	uspto-grants-2004_06
ORD ID	ord-76a0a9883cd14d548c2a1bc55f612627
Source note	uspto-grants-2004_06