Potassium Carbonate → HCID 9869996, compound

Participants

Reaction Steps

A solution of the product from Step 5 (111 mg, 0.17 mmol) and potassium carbonate (7.5 equiv.) in 10 mL of methanol was heated at 50° C. for 48 hrs. The mixture was concentrated to a solid. This solid was chromatographed on silica gel using 1% MeOH/methylene chloride to 20% MeOH/methylene chloride as the gradient eluant to yield the desired product which was then made into the its hydrochloride salt with hydrogen chloride in dioxane.

Provenance & Evidence