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HRID354187

反应详情

EQUATION

反应方程式

HRID 354187 的结构方程式

REACTANTS

反应物

2
结构：Nc1noc(C2CN3CCC2C3)n1
HCID163938

未命名化合物

结构：CCCc1c2nc(-c3cc(C(N)=NOC(C)=O)cnc3OCC(C)C)[nH]c(=O)c2nn1C
HCID136388377

未命名化合物

PRODUCTS

生成物

1
结构：CCCc1c2nc(-c3cc(-c4noc(C)n4)cnc3OCC(C)C)[nH]c(=O)c2nn1C
HCID135730614

未命名化合物

收率 38.1%

PROCEDURE

实验过程

5-{5-[[(Acetyloxy)imino](amino)methyl]-2-isobutoxy-3-pyridinyl}-2-methyl-3-propyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (Example 40) (55 mg, 0.13 mmol) was heated at 190° C. for 3 h. After cooling the oxadiazole was purified by flash column chromatography (elution with 50:1 dichloromethane:methanol) to give 21 mg of a yellow solid.

WORKUP

后处理

  1. customwas purified by flash column chromatography (elution with 50:1 dichloromethane:methanol)