Methyl iodide → 2-[2,4-Dichloro-5-(1-methylethoxy)phenyl]-4,6-dimethyl-1,2,4-triazine-3,5(2H,4H)-dione

Participants

Role	Name	HCID	Charge
Reactant	Methyl iodide	HCID 6328	—
Reactant	Allyl bromide	HCID 7841	—
Reactant	1-Chloro-3-fluoropropane	HCID 11829371	—
Reactant	2-[2,4-dichloro-5-(1-methylethoxy)phenyl]-6-methyl-4-(2-propenyl)-1,2,4-triazine-3,5(2H,4H)-dione	HCID 14276948	—
Reactant	2-[4-chloro-2-fluoro-5-(1-methylethoxy)phenyl]-4-(3-fluoropropyl)-1,2,4-triazine-3,5(2H,4H)-dione	HCID 14276970	—
Reactant	HCID 14747824	HCID 14747824	—
Product	2-[2,4-Dichloro-5-(1-methylethoxy)phenyl]-4,6-dimethyl-1,2,4-triazine-3,5(2H,4H)-dione	HCID 14747830	—

Reaction Steps

Compound 16, 2-[2,4-dichloro-5-(1-methylethoxy)phenyl]-6-methyl-4-(2-propenyl)-1,2,4-triazine-3,5(2H,4H)-dione, was also prepared by the method of Example IV using 3-bromo-1-propene rather than iodomethane in Step D. Similarly, Compound 50, 2-[4-chloro-2-fluoro-5-(1-methylethoxy)phenyl]-4-(3-fluoropropyl)-1,2,4-triazine-3,5(2H,4H)-dione, was prepared by treating Compound 17 (Example II D) with 1-chloro-3-fluoropropane.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04766233
Source dataset	uspto-grants-1988_08
ORD ID	ord-a8a4e6b860b74743ade814dcfb47518e
Source note	uspto-grants-1988_08