4-Methoxybenzaldehyde → Cyclohexyl-(4-methoxyphenyl)methanol

Participants

Reaction Steps

Referring now to FIG. 2, this alternative synthesis starts from 4-methoxy-benzaldehyde (VI) which is subjected to treatment with cyclohexyl magnesium bromide to yield cyclohexyl-(4-methoxy-phenyl)-methanol (V). This in turn is then oxidised so as to yield cyclohexyl-(4-methoxy-phenyl)-methanone (III).

Provenance & Evidence