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HRID35437

反应详情

EQUATION

反应方程式

HRID 35437 的结构方程式

REACTANTS

反应物

1
结构：CC(C)(NC(=O)OCc1ccccc1)C(=O)OC1C(C)(C)CCC1(C)C
HCID54425997

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(N)C(=O)OC1C(C)(C)CCC1(C)C
HCID54251388

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

N-Cbz-2-aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl ester is dissolved in CH3OH and hydrogenated over 10% Pd/C in a Paar hydrogenation apparatus. When the reaction is complete the mixture is filtered through Celite and concentrated to yield 2-aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl ester (600 mg).

WORKUP

后处理

  1. filtrationis filtered through Celite
  2. concentrationconcentrated