Ammonia → HCID 86738800, compound

HRID 354530Notes

Reaction equation

HRID 354530 reaction equation
Cl.Cl.[OH:3][CH:4]([CH3:26])[CH2:5][NH:6][CH2:7][CH2:8][NH:9][C:10]1[CH:23]=[CH:22][C:21]2[C:20](=[O:24])[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:13](=[O:25])[C:12]=2[CH:11]=1.N>CO>[OH:3][CH:4]([CH3:26])[CH2:5][NH:6][CH2:7][CH2:8][NH:9][C:10]1[CH:23]=[CH:22][C:21]2[C:20](=[O:24])[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:13](=[O:25])[C:12]=2[CH:11]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 86738801HCID 86738801, compound

Product 1

HCID 86738800HCID 86738800, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 6.0 g (5.5 mmol) of 1,4-dihydroxy-5,8-bis[2-[(2-hydroxypropylamino)ethylamino]anthraquinone dihydrochloride (which was prepared according to the procedures in Example 32 of U.S. Pat. No. 4,197,249) and 60 ml of methanol may be treated with anhydrous ammonia according to the procedure of Example 1 to yield free base 301, 1,4-dihydroxy-5,8-bis[2-[(2-hydroxypropylamino)ethylamino]-anthraquinone.

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-35fe4d09f19f40fa9ee3d0083b5b9a8b
Source dataset
uspto-grants-1983_03
Patent number
US04375469

Reaction notes

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