HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 3-bromo-2,6-dimethylbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 2,6-Dimethylbenzoic acid | HCID 12439 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 3-bromo-2,6-dimethylbenzoic acid | HCID 8167142 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-bromo-2,6-dimethylbenzoic acid | HCID 8167142 | — |
| Product | methyl 3-bromo-2,6-dimethylbenzoate | HCID 13135243 | — |
Reaction Steps
3-Bromo-2,6-dimethylbenzoic acid was prepared from 2,6-dimethylbenzoic acid by treatment with bromine in acetic acid; see Org. Synth. Coll., Vol. 3, 138 (1944). 3-Bromo-2,6-dimethylbenzoic acid was esterified with methyl iodide as described in Tet. Letters, 689 (1973) to give methyl 3-bromo-2,6-dimethylbenzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04375476 |
| Source dataset | uspto-grants-1983_03 |
| ORD ID | ord-f2da8eec490d41fa982c806b41cc61d4 |
| Source note | uspto-grants-1983_03 |