反应详情

5,6-Dichloro-1-ethyl-2-methylbenzimidazole (11.5 g., 0.05 moles) and 1,4-dibromo-2-butyne (31 g., 0.15 moles) were mixed together and stirred at room temperature overnight. The reaction mixture was treated with ether, the solid was collected by filtration, washed with ether and dried. It was recrystallized from acetonitrile containing 5% water (400 ml). The product was recovered in two crops. Yield 20.2 g (92%), mp. 185°-189° C.

1. filtrationthe solid was collected by filtration
2. washwashed with ether
3. customdried
4. customIt was recrystallized from acetonitrile containing 5% water (400 ml)
5. customThe product was recovered in two crops