Hydrochloric Acid → HCID 15916793, compound

Participants

Reaction Steps

Dissolve 5.3 g of the product of Step B in 50 ml of 80% aqueous ethanol, then add 2.02 g of carbon disulfide and reflux the mixture for one (1) hour. Cool the solution then treat with 0.2 ml of concentrated hydrochloric acid and reflux the mixture for sixteen (16) hours. Concentrate the reaction mixture in vacuo, extract with methylene chloride and dry the extract. Concentrate the extract to a residue and triturate with isopropyl ether to obtain the product of this step. Yield 5.2 g M.P. 104°-106° C. Recrystallize the product from ethanol petroleum ether to obtain the product as a colorless solid. M.P. 105°-106°.

Provenance & Evidence