HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(o-chlorophenyl)-1,3-dihydro-1,3,3-trimethyl-7-nitro-2H-1,4-benzodiazepin-2-one → 5-(o-chlorophenyl)-1,3-dihydro-3,3-dimethyl-7-nitro-2H-1,4-benzodiazepin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(o-chlorophenyl)-1,3-dihydro-1,3,3-trimethyl-7-nitro-2H-1,4-benzodiazepin-2-one | HCID 20506153 | — |
| Reactant | 5-(o-fluorophenyl)-1,3-dihydro-1,3,3-trimethyl-7-nitro-2H-1,4-benzodiazepin-2-one | HCID 20506156 | — |
| Solvent | Dichloromethane ethylacetate | HCID 21226138 | — |
| Product | 5-(o-chlorophenyl)-1,3-dihydro-3,3-dimethyl-7-nitro-2H-1,4-benzodiazepin-2-one | HCID 20506168 | — |
Reaction Steps
From 59 g (0.17 mol) of 5-(o-chlorophenyl)-1,3-dihydro-3,3-dimethyl-7-nitro-2H-1,4-benzodiazepin-2-one there is obtained, in analogy to the details in paragraph (c) of Example 1, 5-(o-chlorophenyl)-1,3-dihydro-1,3,3-trimethyl-7-nitro-2H-1,4-benzodiazepin-2-one of melting point 125°-127° (methylene chloride/ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04377522 |
| Source dataset | uspto-grants-1983_03 |
| ORD ID | ord-7e3c9c7c492643509d526f7cf6689ac3 |
| Source note | uspto-grants-1983_03 |