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HRID354749

反应详情

EQUATION

反应方程式

HRID 354749 的结构方程式

REACTANTS

反应物

2
结构：CN1C(=O)C(C)(C)N=C(c2ccccc2Cl)c2c1ccc(NC(=O)NCCO)c2Br
HCID20506137

未命名化合物

结构：CN1C(=O)C(C)(C)N=C(c2ccccc2Cl)c2c1ccc(N=C=O)c2Br
HCID20506177

未命名化合物

PRODUCTS

生成物

1
结构：CN1C(=O)C(C)(C)N=C(c2ccccc2Cl)c2c1ccc(N)c2Br
HCID20506136

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O.CCOCC
溶剂HCID21584533

Acetone diethylether

C7H16O2

PROCEDURE

实验过程

From 4.5 g (0.011 mol) of 7-amino-6-bromo-5-(o-chlorophenyl)-1,3-dihydro-1,3,3-trimethyl-2H-1,4-benzodiazepin-2-one there is obtained, in analogy to the details in Example 4, via [6-bromo-5-(o-chlorophenyl)-2,3-dihydro-1,3,3-trimethyl-2-oxo-1H-1,4-benzodiazepin-7-yl]isocyanate, 1-[6-bromo-5-(o-chlorophenyl)-2,3-dihydro-1,3,3-trimethyl-2-oxo-1H-1,4-benzodiazepin-7yl]-3-(2-hydroxyethyl)urea of melting point 214°-218° (acetone/ether).