HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water ethanol → 5-(o-chlorophenyl)-1-(2-diethylaminoethyl)-1,3-dihydro-3,3-dimethyl-7-nitro-2H-1,4-benzodiazepin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water ethanol | HCID 19096565 | — |
| Reactant | 7-amino-5-(o-chlorophenyl)-1-(2-diethylaminoethyl)-1,3-dihydro-3,3-dimethyl-2H-1,4-benzodiazepin-2-one | HCID 20506174 | — |
| Product | 5-(o-chlorophenyl)-1-(2-diethylaminoethyl)-1,3-dihydro-3,3-dimethyl-7-nitro-2H-1,4-benzodiazepin-2-one | HCID 20506148 | — |
Reaction Steps
From 10 g (0.022 mol) of 5-(o-chlorophenyl)-1-(2-diethylaminoethyl)-1,3-dihydro-3,3-dimethyl-7-nitro-2H-1,4-benzodiazepin-2-one there is obtained, in analogy to the details in Example 2, 7-amino-5-(o-chlorophenyl)-1-(2-diethylaminoethyl)-1,3-dihydro-3,3-dimethyl-2H-1,4-benzodiazepin-2-one of melting point 70° (ethanol/water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04377522 |
| Source dataset | uspto-grants-1983_03 |
| ORD ID | ord-9cd4dd035e97460dad681c8d8045ffd4 |
| Source note | uspto-grants-1983_03 |