Thionyl Chloride → HCID 178488847, compound

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of 0.006 mole (1.5 g) of 9-methoxyphenazine-1-carboxylic acid and 0.006 mole (0.61 g) of 5-aminotetrazole monohydrate in 50 ml of pyridine was added dropwise 0.012 mole (1.4 g) of thionyl chloride. The mixture was warmed to 70° C., maintained at 70° C. for 20 minutes, then diluted with water. A solid product was separated from the mixture by filtration, washed with water and acetone, and dried. Recrystallization from N,N-dimethylformamide provided 9-methoxy-(N-tetrazol-5-yl)phenazine-1-carboxamide, in the form of orange needles, m.p. 325°-330° C. (dec.)

Provenance & Evidence