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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 354800Generated: October 30, 2026

Fluorobenzene → 4-(4-Phenoxypiperidinyl)-2-phenylquinazoline

https://huagongshe.com/reaction/354800

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFluorobenzeneHCID 10008—
ReactantSodium hydrideHCID 24758—
Reactant1-(2-Phenyl-4-quinazolinyl)-4-piperidinolHCID 12796030—
SolventDimethylformamideHCID 6228—
Product4-(4-Phenoxypiperidinyl)-2-phenylquinazolineHCID 20506473—

Reaction Steps

Equimolar quantities of 4-(4-hydroxypiperidinyl-2-phenylquinazoline, sodium hydride, and fluorobenzene are heated in dimethylformamide to prepare the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04377582
Source datasetuspto-grants-1983_03
ORD IDord-f87f2cf901e847b9a89111e22ac49735
Source noteuspto-grants-1983_03