HCID 54115580, compound → HCID 56627734, compound

Participants

Reaction Conditions

Reaction Steps

29 mg (0.1 mmole) of 4-butyl-5-(6-methoxycarbonyl-2-hexynylidene)-3-hydroxycyclopentanone was dissolved in a mixture of 1 ml of acetic acid, 0.5 ml of tetrahydrofuran and 0.5 ml of water and the solution was stirred at 50° C. for 18 hours in the same way as in Example 1. The reaction mixture was worked up and separated in the same way as in Example 7 to give 13 mg (0.047 mmole; 47% yield) of 4-butyl-5-(6-methoxycarbonyl-2-hexynylidene)-2-cyclopentenone. The resulting compound had the following spectral data.

Provenance & Evidence