Methanol → HCID 13101029, compound

Participants

Reaction Steps

To a solution of 7.17 g. of 3-methyl-2-methylimino-4-diphenylmethyl-4-thiazolidinol hydrobromide (Example 6) in 300 ml. of methanol:water (2.1 v/v) is added, with stirring, 1.8 ml. of 10 N sodium hydroxide. The mixture is chilled, producing a gum which crystallizes on warming to room temperature. These crystals are collected by filtration, washed with methanol:water (2:1) and dried, giving 2.76 g. of the desired product, m.p. 133°-136° C.

Provenance & Evidence