HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Benzenamine, N-(3-chloropropyl)-2-nitro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-[(2-Nitrophenyl)amino]propan-1-ol | HCID 4312551 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | Benzenamine, N-(3-chloropropyl)-2-nitro- | HCID 10775026 | — |
Reaction Steps
To a stirred mixture of 39.2 parts of 3-(2-nitrophenyl)amino-1-propanol and 225 parts of trichloromethane are added dropwise 35.7 parts of sulfinyl chloride (exothermic reaction: temperature rises to 45° C.) Upon completion, stirring is continued for 6 hours at reflux temperature. The reaction mixture is evaporated, yielding N-(3-chloropropyl)-2-nitrobenzenamine as a residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04377578 |
| Source dataset | uspto-grants-1983_03 |
| ORD ID | ord-d04e4534774a48568d3fd6b15d9e128a |
| Source note | uspto-grants-1983_03 |