Acetic Acid → HCID 20443959, compound

Participants

Reaction Steps

A mixture of 1.7 g (0.0042 mole) of p-iodophenacylpyridinium bromide, 0.88 g (0.0042 mole) of p-chlorobenzoylacrylic acid, 2.44 g of ammonium acetate, 5 ml of methanol, 4 ml of acetic acid, and 0.4 ml of acetic anhydride is stirred at reflux for 1.25 hr. 10 ml of methanol is added and the mixture is cooled and the solid is collected. The solid is recrystallized from methanol-acetic acid-water to yield 0.90 g (49%) of the titled crystals with a melting point of 286°-287° C. The C:H:N ratio is 49.67:2.68:3.24.

Provenance & Evidence