Acetic Acid → HCID 20443948, compound

Participants

Reaction Steps

A mixture of 8.65 g (0.026 mole) of the appropriate pyridinium salt, 5.25 g (0.025 mole) of p-chlorobenzoylacrylic acid and 13.5 g of ammonium acetate in 25 ml of methanol, 25 ml of glacial acetic acid, and 5 ml of acetic anhydride is heated at reflux for 2.5 hr. The mixture is worked up as in the preceding Examples and recrystallized from methanol:acetic acid:water to yield 2.4 g (26%) of the titled crystals with melting point of 209°-210° C. The C:H:N ratio is 72.19:5.54:3.95.

Provenance & Evidence