HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 8-[3-(3-Chlorophenyl)-2-oxo-benzimidazolin-1-yl]-caprylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Methyl 8-bromooctanoate | HCID 11107373 | — |
| Reactant | 1-(3-Chlorophenyl)-benzimidazolin-2-one | HCID 20191666 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 8-[3-(3-Chlorophenyl)-2-oxo-benzimidazolin-1-yl]-caprylic acid methyl ester | HCID 12961173 | — |
Reaction Steps
The product is produces as described in example 1 from 1.2 g. of NaH (80% suspension in mineral oil), 9.8 g. of 1-(3-chlorophenyl)-benzimidazolin-2-one, 80 cc. of DMF, 9.5 g. of 8-bromocaprylic acid methyl ester and 1.2 g. of NaJ.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04377695 |
| Source dataset | uspto-grants-1983_03 |
| ORD ID | ord-7468b507969d40f5a1f52fd93840d01c |
| Source note | uspto-grants-1983_03 |