Sodium Hydroxide → 8-(6-Methyl-2-oxo-benzoxazolin-3-yl)-caprylic acid

HRID 355054Notes

Reaction equation

HRID 355054 reaction equation
C[O:2][C:3](=[O:22])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[C:15]2[CH:16]=[CH:17][C:18]([CH3:20])=[CH:19][C:14]=2[O:13][C:12]1=[O:21].[OH-].[Na+]>>[CH3:20][C:18]1[CH:17]=[CH:16][C:15]2[N:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:22])=[O:2])[C:12](=[O:21])[O:13][C:14]=2[CH:19]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 541327788-(6-Methyl-2-oxo-benzoxazolin-3-yl)-caprylic acid methyl ester

Product 1

HCID 129611688-(6-Methyl-2-oxo-benzoxazolin-3-yl)-caprylic acid

Procedure

The product is produced as described in example 22 from 31 g. of 8-(6-methyl-2-oxo-benzoxazolin-3-yl)-caprylic acid methyl ester and 4.4 g. of NaOH. Eluant in chromatographic purification: chloroform.

Workup

  1. customThe product is produced
  2. customEluant in chromatographic purification

Sources & evidence

ORD record
ord-9cfbb9199e23484db5ba8c45740031db
Source dataset
uspto-grants-1983_03
Patent number
US04377695

Reaction notes

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