Sodium Hydroxide → 8-(5-Chloro-2-oxo-benzoxazolin-3-yl)-caprylic acid

HRID 355055Notes

Reaction equation

HRID 355055 reaction equation
C[O:2][C:3](=[O:22])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[C:15]2[CH:16]=[C:17]([Cl:20])[CH:18]=[CH:19][C:14]=2[O:13][C:12]1=[O:21].[OH-].[Na+]>>[Cl:20][C:17]1[CH:18]=[CH:19][C:14]2[O:13][C:12](=[O:21])[N:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:22])=[O:2])[C:15]=2[CH:16]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 129611658-(5-Chloro-2-oxo-benzoxazolin-3-yl)-caprylic acid methyl ester

Product 1

HCID 129611698-(5-Chloro-2-oxo-benzoxazolin-3-yl)-caprylic acid

Procedure

The product is produced as described in example 22 from 10.9 g. of 8-(5-chloro-2-oxo-benzoxazolin-3-yl)-caprylic acid methyl ester and 1.6 g. of NaOH. Eluant in chromatographic purification: chloroform.

Workup

  1. customThe product is produced
  2. customEluant in chromatographic purification

Sources & evidence

ORD record
ord-14423777a58d452b8b5a43510dcb0cd5
Source dataset
uspto-grants-1983_03
Patent number
US04377695

Reaction notes

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