Sodium Hydroxide → 8-[3-(3-Chlorophenyl)-2-oxo-benzimidazolin-1-yl]-caprylic acid

HRID 355062Notes

Reaction equation

HRID 355062 reaction equation
C[O:2][C:3](=[O:28])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[N:13]([C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([Cl:26])[CH:21]=2)[C:12]1=[O:27].[OH-].[Na+]>>[Cl:26][C:22]1[CH:21]=[C:20]([N:13]2[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[N:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:28])=[O:2])[C:12]2=[O:27])[CH:25]=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 129611738-[3-(3-Chlorophenyl)-2-oxo-benzimidazolin-1-yl]-caprylic acid methyl ester

Product 1

HCID 129611808-[3-(3-Chlorophenyl)-2-oxo-benzimidazolin-1-yl]-caprylic acid

Procedure

The product is produced as described in example 22 from 9.3 g. of 8-[3-(3-chlorophenyl)-2-oxo-benzimidazolin-1-yl]-caprylic acid methyl ester and 2.56 g. of NaOH.

Workup

  1. customThe product is produced

Sources & evidence

ORD record
ord-5783899fc5904a81abb695c2510c5dee
Source dataset
uspto-grants-1983_03
Patent number
US04377695

Reaction notes

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