Sodium Hydroxide → 8-(3-Benzyl-2-oxo-benzimidazolin-1-yl)-caprylic acid
Reaction equation
C[O:2][C:3](=[O:28])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[N:13]([CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:12]1=[O:27].[OH-].[Na+]>>[CH2:20]([N:13]1[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[N:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:28])=[O:2])[C:12]1=[O:27])[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1Participants
3
Procedure
The product is produced as described in example 22 from 4.3 g. of 8-(3-benzyl-2-oxo-benzimidazolin-1-yl)-caprylic acid methyl ester and 0.5 g. of sodium hydroxide.
Workup
- customThe product is produced
Sources & evidence
- ORD record
- ord-7eb7fe2811ca430185bdb600afcbfa1f
- Source dataset
- uspto-grants-1983_03
- Patent number
- US04377695
Reaction notes
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