Sodium Hydroxide → 8-[3-(4-Fluorobenzyl)-2-oxo-benzimidazolin-1-yl]-caprylic acid

HRID 355066Notes

Reaction equation

HRID 355066 reaction equation
C[O:2][C:3](=[O:29])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[N:13]([CH2:20][C:21]2[CH:26]=[CH:25][C:24]([F:27])=[CH:23][CH:22]=2)[C:12]1=[O:28].[OH-].[Na+]>>[F:27][C:24]1[CH:23]=[CH:22][C:21]([CH2:20][N:13]2[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[N:11]([CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:29])=[O:2])[C:12]2=[O:28])=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 12961175HCID 12961175, compound

Product 1

HCID 129611848-[3-(4-Fluorobenzyl)-2-oxo-benzimidazolin-1-yl]-caprylic acid

Procedure

The product is produced as described in example 22 from 7.5 g. of 8-[3-(4-fluorobenzyl)-2-oxo-benzimidazolin-1-yl]-caprylic acid methyl ester and 1.5 g. of NaOH.

Workup

  1. customThe product is produced

Sources & evidence

ORD record
ord-a058b97d2fca474eaae2c8c2d6367d2a
Source dataset
uspto-grants-1983_03
Patent number
US04377695

Reaction notes

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