2-Bromo-5-(chlorosulfonyl)benzoic acid → HCID 20505966, compound

HRID 355126Notes

Reaction equation

HRID 355126 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][C:8]([S:11](Cl)(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH2:15]([O:22][CH:23]1[CH2:28][CH2:27][CH2:26][NH:25][CH2:24]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[Br:1][C:2]1[CH:10]=[CH:9][C:8]([S:11]([N:25]2[CH2:26][CH2:27][CH2:28][CH:23]([O:22][CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:24]2)(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]

Participants

3

Reactant 2

HCID 34272982-Bromo-5-(chlorosulfonyl)benzoic acidHCID 199606043-(Benzyloxy)piperidine

Product 1

HCID 20505966HCID 20505966, compound

Procedure

2-Bromo-5-chlorosulfonylbenzoic acid is reacted with 3-benzyloxypiperidine by the method of Example 1. Recrystallization from ether-hexane, yields the product, m.p. 177°-178° C.

Workup

  1. customRecrystallization from ether-hexane
  2. customyields the product, m.p. 177°-178° C.

Sources & evidence

ORD record
ord-09fb26f93d8c461e85c8867a503f8e60
Source dataset
uspto-grants-1983_03
Patent number
US04377521

Reaction notes

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