4-Fluoro-3-(1-piperidinylsulfonyl)benzoic acid → 381229-72-7

HRID 355142Notes

Reaction equation

HRID 355142 reaction equation
[F:1][C:2]1[C:10]([S:11]([N:14]2[CH2:19]CCC[CH2:15]2)(=[O:13])=[O:12])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.ClC1C(S(N2CC(C)CC(C)C2)(=O)=O)=CC(C(O)=O)=CC=1.ClC1C(S(N2CCOCC2)(=O)=O)=CC(C(O)=O)=CC=1.ClC1C(S(N2CCCC(C)C2)(=O)=O)=CC(C(O)=O)=CC=1.BrC1C(S(NCC2C=CC(Cl)=CC=2)(=O)=O)=CC(C(O)=O)=CC=1.CC1C(S(N2CCC(C)(C)CC2)(=O)=O)=CC(C(O)=O)=CC=1.CC1C(S(NC2C=C(Br)C=C(Br)C=2)(=O)=O)=CC(C(O)=O)=CC=1.CC1C(S(NCCCC2C=CC=CC=2)(=O)=O)=CC(C(O)=O)=CC=1.COC1C(S(N2CCC(C)CC2C)(=O)=O)=CC(C(O)=O)=CC=1.COC1C(S(N(C(C)C)C(C)C)(=O)=O)=CC(C(O)=O)=CC=1>>[F:1][C:2]1[C:10]([S:11]([N:14]([CH3:19])[CH3:15])(=[O:13])=[O:12])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1

Participants

11

Reactant 10

HCID 6832524-Fluoro-3-(1-piperidinylsulfonyl)benzoic acidHCID 7679004-Chloro-3-(morpholine-4-sulfonyl)-benzoic acidHCID 50038664-CHLORO-3-(3-METHYL-PIPERIDINE-1-SULFONYL)-BENZOIC ACIDHCID 20505834HCID 20505834, compoundHCID 20505850HCID 20505850, compoundHCID 20505876HCID 20505876, compoundHCID 20505974HCID 20505974, compoundHCID 20505995HCID 20505995, compoundHCID 20506059HCID 20506059, compoundHCID 20506116HCID 20506116, compound

Product 1

HCID 11118373381229-72-7

Procedure

4-fluoro-5-piperidinosulfonylbenzoic acid; 4-chloro-5-(3,5-dimethylpiperidinosulfonyl)benzoic acid; 4-chloro-5-morpholinosulfonylbenzoic acid; 4-chloro-5-(3-methylpiperidinosulfonyl)benzoic acid; 4-bromo-5-hexamethyleneiminosulfonylbenzoic acid; 4-bromo-5-(4-chlorobenzylaminosulfonyl)benzoic acid; 4-methyl-5-(4,4-dimethylpiperidinosulfonyl)benzoic acid; 4-methyl-5-(3,5-dibromophenylaminosulfonyl)-benzoic acid; 4-methyl-5-(3-phenylpropylaminosulfonyl)benzoic acid; 4-methoxy-5-(2,4-dimethylpiperidinosulfonyl)benzoic acid; 4-methoxy-5-(4-biphenylethylaminosulfonyl)benzoic acid; 4-methoxy-5-(2-p-bromophenethylaminosulfonyl)-benzoic acid; and 4-methoxy-5-di-i-propylaminosulfonylbenzoic acid.

Sources & evidence

ORD record
ord-255b909c896444b7aadfe0224c006e2b
Source dataset
uspto-grants-1983_03
Patent number
US04377521

Reaction notes

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