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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 355150Generated: October 26, 2026

1H-Indole, 2-propyl- → 3,5-bis(1-n-propyl-2-methyl-3-indolyl)-5-(1-ethyl-2-methyl-3-indolyl)-2(5H)-furanone

https://huagongshe.com/reaction/355150

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Indole, 2-propyl-HCID 139415—
Reactant1H-Indole, 1-ethyl-2-methyl-HCID 170432—
Reactant2,4-Bis(6-chloro-2-phenyl-3-indolyl)-4-oxobutanoic acidHCID 20442741—
Product3,5-bis(1-n-propyl-2-methyl-3-indolyl)-5-(1-ethyl-2-methyl-3-indolyl)-2(5H)-furanoneHCID 54027974—

Reaction Steps

Following a procedure similar to that described above in part B of this example by using 2,4-bis(6-chloro-2-phenyl-3-indolyl)-4-oxobutanoic acid instead of 2,4-bis(1-n-propyl-2-methyl-3-indolyl)-4-oxobutanoic acid, and 2-propylindole is substituted for 1-ethyl-2-methylindole, there is obtained 3,5-bis-(6-chloro-2-phenyl-3-indolyl)-5-(2-propyl-3-indolyl-2(5H)-furanone (Formula III: R=R2 =Y1 =H; R1 =C6H5 ; R3 =CH3CH2CH2 ; Y=6-Cl).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04377698
Source datasetuspto-grants-1983_03
ORD IDord-d15e1b9e5a1a45ba84b6984ddf7a6f38
Source noteuspto-grants-1983_03