HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzyl Alcohol → 4-Hydroxybenzyl cyanide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzyl Alcohol | HCID 125 | — |
| Reactant | Ethyl formate | HCID 8025 | — |
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Hydroxybenzyl cyanide | HCID 26548 | 94% |
Reaction Steps
A mixture of 4.96 g. para-hydroxybenzyl alcohol 2.4 g. sodium cyanide 12 ml. ethanol and 12 ml. ethyl formate is heated with stirring under reflux for a period of ninety minutes. The reaction product is then subjected to the same isolation process as in Example 1 to give a 94% yield of crude product showing a melting point of 58°-61° C. uncorrected.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04378319 |
| Source dataset | uspto-grants-1983_03 |
| ORD ID | ord-5b26fe9aa1ff4ab9b2b5955441ade8de |
| Source note | uspto-grants-1983_03 |