Thionyl Chloride → HCID 86736784, compound

HRID 355187Notes

Reaction equation

HRID 355187 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]([C:13]([F:16])([F:15])[F:14])=[CH:4][C@H:5]1[C@H:7]([C:8](O)=[O:9])[C:6]1([CH3:12])[CH3:11].S(Cl)([Cl:21])=O>>[Cl:21][C:8]([C@H:7]1[C@H:5]([CH:4]=[C:3]([C:13]([F:16])([F:15])[F:14])[C:2]([F:18])([F:17])[F:1])[C:6]1([CH3:12])[CH3:11])=[O:9]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 86736785HCID 86736785, compound

Product 1

HCID 86736784HCID 86736784, compound

Procedure

A mixture of (+)-cis/trans-3-(3,3,3-trifluoro-2-trifluoromethyl-prop-1-en-1-yl)-2,2-dimethylcyclopropane carboxylic acid (0.4 g) and thionyl chloride (5.0 ml) was heated at the reflux temperature for a period of 2 hours, after which the excess thionyl chloride was removed by distillation under reduced pressure, leaving (+)-cis/trans-1-chlorocarbonyl-3-(3,3,3-trifluoro-2-trifluoromethyl-prop-1-en-1-yl)-2,2-dimethylcyclopropane.

Workup

  1. temperaturewas heated at the reflux temperature for a period of 2 hours
  2. customafter which the excess thionyl chloride was removed by distillation under reduced pressure

Sources & evidence

ORD record
ord-632793545948425f86798f488f83eaf0
Source dataset
uspto-grants-1983_03
Patent number
US04378316

Reaction notes

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