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HRID355511

反应详情

EQUATION

反应方程式

HRID 355511 的结构方程式

REACTANTS

反应物

1
结构：CC(=O)OC[C@H]1O[C@@H](n2cnc(C(=O)OC(C)(C)C)c2N2C(=O)c3ccccc3C2=O)[C@H](Cl)[C@@H]1OC(C)=O
HCID57307244

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CC(=O)OC[C@H]1O[C@@H](n2cnc(C(=O)O)c2N2C(=O)c3ccccc3C2=O)[C@H](Cl)[C@@H]1OC(C)=O
HCID53998996

未命名化合物

收率 97%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl.O=C(O)C(F)(F)F
溶剂HCID21863450

未命名化合物

PROCEDURE

实验过程

Compound (34) obtained in step (2) above (1.50 g) was dissolved in a mixture of trifluoroacetic acid-dichloromethane (1:4) (25 ml), and the solution so obtained was allowed to stand at room temperature overnight so that there occurred de-esterification of compound (34). The resulting reaction solution was concentrated to leave a solid. This solid was then washed with diethyl ether to yield the titled compound (35) (1.31 g) which was insoluble in diethyl ether (1.31 g). Yield: 97%.

WORKUP

后处理

  1. customthe solution so obtained
  2. customThe resulting reaction solution
  3. concentrationwas concentrated
  4. customto leave a solid
  5. washThis solid was then washed with diethyl ether