HCID 57255716, compound → HCID 123959124, compound

HRID 355536Notes

Reaction equation

HRID 355536 reaction equation
C([O:8][C:9](=[O:23])[C@@H:10]([CH2:21][NH2:22])[C@H:11]([O:13][Si:14]([C:17]([CH3:20])([CH3:19])[CH3:18])(C)[CH3:15])[CH3:12])C1C=CC=CC=1>[Pd]>[NH2:22][CH2:21][C@@H:10]([C@H:11]([O:13][SiH:14]([C:17]([CH3:18])([CH3:20])[CH3:19])[CH3:15])[CH3:12])[C:9]([OH:23])=[O:8]

Participants

3

Reactant 1

HCID 57255716HCID 57255716, compound

Product 1

HCID 123959124HCID 123959124, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

subjecting (2S, 3R)-2-aminomethyl-3- (tert-butyldimethylsilyloxy)butanoic acid benzyl ester to catalytic hydrogenation in the presence of the palladium catalyst under hydrogen atmosphere to give (2S, 3R)-2-aminomethyl-3-(tert-butylmethylsilyloxy)butanoic acid, and

Sources & evidence

ORD record
ord-a04339d0def84941bc4f50d6432341b4
Source dataset
uspto-grants-1998_11
Patent number
US05831091

Reaction notes

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