Acetophenone → 1-Phenylethanol

HRID 355543Notes

Reaction equation

HRID 355543 reaction equation
Cl.[Al].[Mg].[Cl].[C:5]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)(=[O:7])[CH3:6]>>[C:8]1([CH:5]([OH:7])[CH3:6])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 7410AcetophenoneHCID 178477807HCID 178477807, compound

Product 1

HCID 74091-PhenylethanolYield 95%

Procedure

Repeating the procedure of Example 2, 22.4 g (11.2 mmoles) of chlorine magnesium aluminum hydridochloride solution are reacted with 1.81 g (15 mmoles) of acetophenone. After the reaction product is worked up, 1 H-NMR spectroscopy confirms a 95% yield of 1-phenylethanol.

Sources & evidence

ORD record
ord-f8ff94649e244df09b5b86858c40598a
Source dataset
uspto-grants-1998_11
Patent number
US05831103

Reaction notes

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