HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 355593Generated: October 30, 2026
Acetone Cyanohydrin → 2-((4-Hydroxybutyl)amino)-2-methylpropanenitrile
https://huagongshe.com/reaction/355593
Participants
| Role | Name | HCID | Charge |
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| Reactant | Acetone Cyanohydrin | HCID 6406 | — |
| Reactant | 4-Amino-1-butanol | HCID 25868 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-((4-Hydroxybutyl)amino)-2-methylpropanenitrile | HCID 15511961 | — |
Reaction Steps
220 μl of acetone cyanohydrin and 200 μl of 4-amino 1-butanol were mixed together with stirring for 16 hours at 20° C. and then was diluted with 2 ml of methylene chloride, dried, filtered and the filtrate was concentrated under reduced pressure to obtain the propanonitrile which was used as is for the following stage.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | USRE035956 |
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| Source dataset | uspto-grants-1998_11 |
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| ORD ID | ord-a3d76543b8e940478ba58e6c12579ee3 |
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| Source note | uspto-grants-1998_11 |
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