Benzoyl chloride → HCID 18940220, compound

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Reaction Steps

2.98 pbw of 2-amino-9-(2,5-dimethylphenyl)acridine (compound 1d) were dissolved in 75 pbv of methylene chloride at 23° C. and 2.1 pbw of benzoyl chloride were gradually added while stirring. The temperature rose to 27°-28° C. during this process. The solution was stirred for 4 hours and, after standing overnight, extracted by shaking with sodium hydroxide solution, and the organic phase was distilled off after drying over anhydrous sodium sulfate. Yield: 3.96 pbw (98% of theory), yellowish green crystals. Mp.: 253°-255° C.

Provenance & Evidence