Water → HCID 18940219, compound

Participants

Reaction Steps

1.42 pbw of the compound 1d and 2.78 pbw of ethyl chloroformate were dissolved in 100 pbv of acetonitrile at 25° C. and 4.85 pbv of N-methylmorpholine were added. The temperature rose to 38° C. during this process. Stirring of the yellow solution was continued for 15 minutes, then it was poured into 400 pbv of water, and the mixture was stirred for 2 hours and the precipitated residue filtered off by suction. Yield: 1.3 pbw (72% of theory). Mp.: 200°-202° C.

Provenance & Evidence