HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → N-[(E,E)-4-ethyl-2,4-hexadienoyloxy]succinimide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | N-Hydroxysuccinimide | HCID 80170 | — |
| Reactant | 4-Ethylhexa-2,4-dienoic acid | HCID 10942523 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | N-[(E,E)-4-ethyl-2,4-hexadienoyloxy]succinimide | HCID 14329790 | 90.6% |
Reaction Steps
To a solution of (E,E)-4-ethyl-2,4-hexadienoic acid (7 g) and N-hydroxysuccinimide (5.75 g) in dioxane (100 ml) was added dicyclohexylcarbodiimide (10.8 g). The mixture was stirred at ambient temperature overnight and then filtered. The filtrate was concentrated under reduced pressure to give a residue which was recrystallized from a mixture of ether and petroleum ether to give N-[(E,E)-4-ethyl-2,4-hexadienoyloxy]succinimide (10.73 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04767768 |
| Source dataset | uspto-grants-1988_08 |
| ORD ID | ord-38ad3984fcb74f87b3d3430852c37cf5 |
| Source note | uspto-grants-1988_08 |