1-Bromo-3-chloropropane → 9-(3-Chloro-1-propyl)-3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-9H-beta-carboline

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Reaction Steps

The compound was synthesized by mixing (Compound 5) (1.0 g, 3.6 mmol), NaH (0.22 g, 4.3 mmol) and 1-bromo-3-chloropropane (0.68 g, 4.3 mmol)in DMF, in the same manner as illustrated in example 3, to give the title compound (0.76 g, 63%) as a white solid. M.p. 165°-169° C.

Provenance & Evidence