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HRID355888

反应详情

EQUATION

反应方程式

HRID 355888 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(C(=O)Cl)c(C)c1
HCID140867

Benzoyl chloride, 2,4-dimethyl-

C9H9ClO

结构：Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)cc1
HCID15410467

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(C(=O)Nc2ccc(C(=O)N3Cc4ccccc4Cc4ccccc43)cc2)c(C)c1
HCID15307977

未命名化合物

收率 56.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

As described in Example 9, 0.471 g (1.5 mmol) of 5-(4-aminobenzoyl)-6,11-dihydro-5H-dibenz[b,e]azepine is reacted with 0.303 g (1.8 mmol) of 2,4-dimethylbenzoyl chloride in 10 ml of dichloromethane. The product is recrystallized from hexane-dichloromethane to give 0.38 g of crystals, m.p. 197°-199° C.

WORKUP

后处理

  1. customThe product is recrystallized from hexane-dichloromethane