1,1-Dibromododecane → 1,1'-(1,12-dodecanediyl)bis(4-(4-methyl-phenyl)-2(1H)-pyridinimine) dihydrobromide

HRID 355944Notes

Reaction equation

HRID 355944 reaction equation
[Br:1][CH:2](Br)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[NH2:15][C:16]1[CH:21]=[C:20]([C:22]2[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][CH:23]=2)[CH:19]=[CH:18][N:17]=1>>[BrH:1].[BrH:1].[CH2:2]([N:17]1[CH:18]=[CH:19][C:20]([C:22]2[CH:23]=[CH:24][C:25]([CH3:28])=[CH:26][CH:27]=2)=[CH:21][C:16]1=[NH:15])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][N:17]1[CH:18]=[CH:19][C:20]([C:22]2[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][CH:23]=2)=[CH:21][C:16]1=[NH:15]

Participants

3

Reactant 2

HCID 113249061,1-DibromododecaneHCID 137770672-Amino-4-(4-methylphenyl)pyridine

Product 1

HCID 676451951,1'-(1,12-dodecanediyl)bis(4-(4-methyl-phenyl)-2(1H)-pyridinimine) dihydrobromide

Procedure

The procedure is as above, with dibromododecane and 2-amino-4-para-tolylpyridine, which is synthesized according to Chambron J.Cl. Strasbourg Tetrah. 1987 43 (5) 895/905. The product obtained is purified in the base state on a silica column with a benzene/ethyl acetate mixture. It is reconverted to the hydrobromide with a mixture of ether and an isopropanol solution of hydrogen bromide. It can then be recrystallized.

Workup

  1. customis synthesized
  2. customThe product obtained
  3. customis purified in the base state on a silica column with a benzene/ethyl acetate mixture
  4. additionIt is reconverted to the hydrobromide with a mixture of ether
  5. customIt can then be recrystallized

Sources & evidence

ORD record
ord-9dada8b2b8234a8b9d4b796da7fd8a1e
Source dataset
uspto-grants-1998_11
Patent number
US05834491

Reaction notes

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