HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,8-Diacetylamino-1-tetralone → 3-Acetylamino-5-amino-8-methyl-2,3-dihydroquinoline-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,8-Diacetylamino-1-tetralone | HCID 12047298 | — |
| Reactant | 1-Acetyl-3,5-diacetylamino-8-methyl-2,3-dihydro-quinoline-4-one | HCID 22449480 | — |
| Product | 3-Acetylamino-5-amino-8-methyl-2,3-dihydroquinoline-4-one | HCID 22449472 | — |
Reaction Steps
The procedure of Example 1-(4) was followed by using 1.40 gm of the compound prepared in (3) above instead of 2,8-diacetylamino-1-tetralone. The reaction product was post-treated to obtain 0.79 gm of the title compound. NMR(CDCl3)δ: 2.01(s, 3H), 2.08(s, 3H), 3.0-4.5(m, 3H), 5.89(d, 1H, J=8 Hz), 6.95(d, 1H, J=8 Hz) 5.7-6.8(br.s, 2H); MASS m/z: 233(M+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05834476 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-340be32089cc4e189c2f2e36be24c3e6 |
| Source note | uspto-grants-1998_11 |